Introducing Liquid Phycocyanin


Phycocyanin is a rare naturally occurring blue pigment found in blue green algae and a small group of bacteria. Phycocyanin is around 3 billion years old and is the ancestor to the green pigment chlorophyll which we see in most plants today. This  pigment is a unique biologically active nutrient compound which is isolated and purified from Arthrospira Platensis more commonly known as Spirulina. Phycocyanin has been scientifically studied all over the world for over 40 years.


It has been well established that  phycocyanin has the following properties: anti-inflammatory, antioxidant, stem cell stimulant, immune system stimulant  and can adjust our sensitivity to pain just to name a few.  

Antioxidant Activity


Over the last 40+ years Phycocyanin has been proven scientifically to be a powerful natural antioxidant. Helping to prevent damage to the body by free radicals, in particular cytotoxic (cell damaging) reactive oxygen species (ROS).

Increased physical activity, cellular repair due to injury or exercise ramps up ATP (cellular fuel) utilisation by our cells creating more energy for the body. However, when there are insufficient antioxidants available (oxidative stress) to neutralise your cells natural exhaust (ROS) from that ATP creation or use, damage can occur.

In sports and in general, this can decrease performance, cause injury, reduce training effectiveness, cause tissue damage, which leads to poor recovery and overtraining syndrome. Phycocyanin can help to balance out these situations and clean up your cell’s emissions preventing or reducing damage.

Inflammation


Unfortunately, at present it is impossible to escape modern pollution. We can only reduce our exposure and combat its effects. These elements are having adverse effects on our health and thus when injured or performing mild or intense exercise, we can potentially have an over expression of inflammation.  This can hinder our healing and our overall physical performance.  

Phycocyanin has been shown to inhibit overexpression of NO and PGE2 by downregulating the expression of iNOS and COX2 and reducing the formation of TNF-a and the infiltration of neutrophils into inflammation sites. So phycocyanin can reduce excessive inflammation by regulating the body's inflammatory response so that it reacts in a more controlled and balanced way in its presence. Having a healthy, balanced and naturally controlled inflammatory response is key to healing, recovery, and physical development.

Stem Cell Production


Phycocyanin can help with recovery and repair. Studies show that phycocyanin stimulates the proliferation of bone marrow cells (Stem Cells) and production of colony-forming activity.

Additionally, phycocyanin can act like the hormone Erythropoietin (EPO) and can stimulate the production of red blood cells which can carry oxygen and nutrients throughout the body to maintain, build and repair.

Anti-Viral Properties


Phycocyanin can increase the quantity and activity of white blood cells (leukocytes), macrophages, and NK cells (Natural Killer). These cells are the main offensives players in our immune system and have the role of eliminating pathogens such as microbes, bacteria and viruses.

Phycocyanin has the ability to bond to a specific part of an RNA virus that is used to consume ATP (cellular fuel). This bonding blocks the fuel line to a specific part of the machinery which allows the virus to connect to our cells and start the viral replication process. Even if the virus started to connect with our cells it cannot complete the process as the final part to do so has no power to run.

Liquid Phycocyanin 150ml

Blue pigment is extremely rare in nature and with all rare things they have unique and valuable properties. The many enhancements to biological functions this collection of pigments can bring is extensive for this brief document. Here are some key benifits and features.

Benefits


  • Over 40 years of clinical research.
  • Natural selective COX2 inhibitor/regulator.
  • Normalises inflammatory response.
  • Helps to balance out oxidative stress reducing cellular, muscle & tissue damage.
  • Aids the reduction of muscle fatigue
  • Stimulates Stem Cells for the production of red blood cells & other cells for repair, maintenance and growth.
  • Immune system stimulant and regulator
  • Protects as well as assists liver & kidney function.
  • Reduces sensitivity to pain.


Features


  • Anti-inflammatory properties does not negatively affect the redox signalling process.
  • Clean and pure product with no fillers or unnecessary additional ingredients.
  • Purification process lets us provide more potence with less algae so less packaging.
  • Does not compete with food crops for its production.


WHO THIS CAN BENEFIT


•   Heath Food Suppliers
•    Nutritionist 
•    Osteopaths
•    Chiropractors
•    Physiotherapist
•    Athletes
•    Sports or Exercise Enthusiast
•  People looking for natural anti- inflammatory, antioxidant, Immune system and stem cells stimulant alternatives

Liquid Phycocyanin 12g/l (60mg/5ml)

Ingredients: purified extract of phycocyanin from Spirulina Platensis concentrated to 12g/l, vegetable glycerine and purified water. Units 150 ml bottle, 30 serving a bottle (60mg/5ml). Mix with a min 200ml water and drink.

Quality & Safety: All our ingredients are subjected to consecutive tests before and after production.  This is done so to verify the quality, stability, and the concentration of the product.

Additionally, for safety and quality assurance we confirm the absence of toxic substances, pesticides, heavy metals, and other foreign substances. These tests are subject to counter-analysis by independent third-party laboratories.

FAST ACTING


Converted into liquid Phycocyanin from powder to rapidly accelerate digestion so you can get it right when you need it



HIGH CONCENTRATION


One of the highest liquid concentrations in the game at 12g/l (12,000 mg/l) 60mg a serving at 5ml  (1 teaspoon). This is further enhanced by a thorough and refined extraction & purification method that has developed over several years.



QUALITY SPIRULINA


Our products are guaranteed to be of natural origin and GMO-free. A third-party laboratory tests the Spirulina’s purity before any processing. Vegan friendly.



BIOAVAILABILITY


The advance purification process fully unlocks the phycocyanin from the cell enabling us to provide a liquid that will allow your body to absorb it quickly and efficiently far beyond the powdered form.

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REFERENCES

 

Action on the Liver


1.      Phycocyanobilin accelerates liverregeneration and reduces mortality rate in carbon tetrachloride-induced liverinjury mice.

 

Jie Liu, Qing-Yu Zhang, Li-Ming Yu, Bin Liu,Ming-Yi Li, and Run-Zhi Zhu

 

[NationalCenter for Biotechnology Information]                  [Pub Med]

 

2.      Protectiveeffects of C-phycocyanin on alcohol-induced acute liver injury in mice

 

Dong Xia , Bing Liu , Xiying Luan , Junyan Sun , NanaLiu , Song Qin & ZhenningDu  ChineseJournal of Oceanology and Limnologyvolume 34, pages399–404 (2016)


[SpringerLink]


3.     Hepatoprotective Effect of C-Phycocyanin: ProtectionforCarbon Tetrachloride andR-(/)-Pulegone-Mediated Hepatotoxicty in Rats


Bhat. B. Vadiraja, Nilesh.W. Gaikwad, and K. M. Madyastha Published 1998Department of Organic Chemistry, Indian Institute of Science, DOI:10.1006/BBRC.1998.9149


[semanticscholar.org]       [PDF]

 


Action on kidneys


1.     Antioxidant property of C-phycocyanin protects therenal cell against oxalate-induced injury and may be a nephroprotective agent. Dr. AL Mudalia – Clin Chim Acta. 2004 Oct; 348 (1-2):199-205.

2.     Phycocyaninand phycocyanobilin from Spirulina platensis protect against diabeticnephropathy by inhibiting oxidative stress.


Jing ZhengToyoshiInoguchiShuji SasakiYasutakaMaedaMark FMcCartyMasakazu FujiiNorikoIkedaKunihisaKobayashiNoriyuki SonodaRyoichiTakayanagi

 

PMID: 23115122       DOI: 10.1152/ajpregu.00648.2011

 

[PDF]  [Pub Med]       [AmericanPhysiological Society Publications]

 

Antioxidant, radical-scavenging action Inflammation

1.     Antioxidant and anti-inflammatory properties of c-phycocyaninextracted from blue-green algae. Romay C, Armesto J, Remirez D, Gonzalez R,Ledon L, Garcia I. Inflamm Res.1998 ; 47 : 36-41.

[Springer Link]           [PDFResearch Gate]

2.   C-phycocyanin: a naturalproduct with radiosensitizing property for enhancement of colon cancerradiation therapy efficacy through inhibition of COX-2 expression


https://doi.org/10.1038/s41598-019-55605-w

3.     Protective effect of aqueous extract fromSpirulina platensis against cell death induced by free radicals. BMCComplementary and Alternative Medicine volume 10, Article number: 53 (2010)

Wan-Loy Chu, Yen-Wei Lim, Ammu KuttyRadhakrishnan & Phaik-Eem Lim

doi:10.1186/1472-6882-10-53

[BMC Complementary and Alternative Medicine]    [PDF]

4.     C-Phycocyanin: A Biliprotein with Antioxidant, Anti-Inflammatoryand Neuroprotective Effects. Current Protein and Peptide Science, 2003, 4,207-216

Ch. Romay*,1, R. González1 , N. Ledón1, D.Remirez1  and V. Rimbau2

PMID: 12769719        DOI: 10.2174/1389203033487216 

[PubMed]      [PDF]

 


Antiviral Action


1.      Well-tolerated Spirulina extract inhibits influenzavirus replication and reduces virus-induced mortality. Published: 12 April 2016

Yi-HsiangChen1,3,Gi-KungChang1, Shu-Ming Kuo1, Sheng-Yu Huang1,3, I-Chen Hu5, Yu-Lun Lo1 &Shin-Ru Shih

ScientificReports | 6:24253 | DOI: 10.1038/srep24253


[Research Gate]          [Nature]          [PDF]


2.     C-Phycocyanin Of SpirulinaPlantesis Inhibits Nsp12 Required For Replication OfSars-Cov-2: A Novel Finding In-Silico

T. Kiran Raj 1, R. Ranjithkumar 2,B. M. Kanthesh 3 and T. S. Gopenath * 1

[IJPSR]          [Research Gate]         [PDF]


3.     Nutraceuticalshave potential for boosting the type 1 interferon response to RNA virusesincluding influenza and coronavirus. Published in Progress in CardiovascularDiseases Volume 63, Issue 3, May–June 2020, Pages 383-385

 

MarkF. McCartya and JamesJ. DiNicolantonio


[National Center for Biotechnology Information]      [PubMed]      [Science Direct]    [PDF]


Activationof the human innate immune system by Spirulina: augmentation of interferonproduction and NK cytotoxicity by oral administration of hot water extract ofSpirulina platensis


TomohiroHirahashi  1 , Misako Matsumoto, KaoruHazeki, Yoshiko Saeki, Michio Ui, Tsukasa Seya

PMID: 11962722DOI: 10.1016/s1567-5769(01)00166-7


Stem Cells


Proliferationand Differentiation of Hematopoietic Cells and Preservation of Immune Functions.Published in Intech September 21st 2012


OsamuHayashi

http://dx.doi.org/10.5772/48322     [Intech Open]              [PDF]



Fertility


1.     Phycocyanin Improves Reproductive Ability inObese Female Mice by Restoring Ovary and Oocyte Quality. Front. Cell Dev.Biol., 13 November 2020

Xin Wen1, Zhe Han1, Shu-Jun Liu1, Xin Hao1,Xiao-Jie Zhang1, Xing-Yue Wang1, Cheng-Jie Zhou1, Yu-Zhen Ma2 and Cheng-GuangLiang1*

Front. Cell Dev. Biol., 13 November 2020 | https://doi.org/10.3389/fcell.2020.595373

 

2.     Phycocyanin protects  against  low fertility  by  inhibiting reactive oxygen species in aging mice. Oncotarget, Vol. 7, No. 14 March17, 2016

Yan-Jiao Li1,  Zhe  Han1, Lei  Ge1,  Cheng-Jie Zhou1,  Yue-Fang  Zhao1, Dong-Hui  Wang1, Jing Ren1,Xin-Xin Niu1 and Cheng-Guang Liang1

https://doi.org/10.18632/oncotarget.8165       [PDF]

 

PhycocyaninSupplementation Safety


1.      ClinicalSafety of a High Dose of Phycocyanin-Enriched Aqueous Extract from Arthrospira(Spirulina) platensis: Results from a Randomized, Double-Blind,Placebo-Controlled Study with a Focus on Anticoagulant Activity and PlateletActivation. 2016 Jun 30

 

Gitte S Jensen  1 , Cassandra Drapeau  2 , Miki Lenninger  1 , Kathleen F Benson  1

PMID: 27362442 PMCID: PMC4948198 DOI:10.1089/jmf.2015.0143

 

[Pub Med]       [Journal ofMedicinal FoodVol. 19, No. 7]    [PDF] 

 

[Foodand Agriculture Organization of the United Nations]